Capsule and tablet turnkey projects, including clean room, power generation, factory planning and design, equipment installation, etc.

Since 2018, we have successively helped customers improve capsule and tablet production lines to create a complete, fast and high-quality production process. According to the factory area, we design a reasonable production line and provide various equipment, including but not optional, capsule filling, blister packaging, mixing, counting, fluidized bed granulation, clean room, soft aluminum packaging, etc.

In 2024, the project was expanded and the customer introduced a new production line, which is being debugged and installed. Strive for more European markets for customers.

1. Clean before production

2.Clean after shift production

In recent years, China's drug demand continues to increase, more and more drugs in a short period of time to achieve the market. At the same time, relevant regulations are also increasingly stringent requirements for pharmaceutical packaging. Recently, the "Industrial Structure Adjustment Guidance Directory (2024)" issued by the National Development and Reform Commission once again proposed that it will continue to encourage the development and production of new pharmaceutical packaging materials and technologies, that is, mixed-use, intelligent packaging and other new packaging systems and drug delivery devices.

In the face of new trends and new policies, China's pharmaceutical packaging machinery enterprises are constantly strengthening research and development and innovation capabilities to create innovative products that meet market demand. With the continuous improvement of the degree of automation of these innovative products, the pharmaceutical packaging field has been transformed and upgraded at a high speed.

As the upstream link of the pharmaceutical packaging industry chain, only modern, efficient, safe and automated can better improve drug production efficiency, safeguard drug safety, and become an indispensable key part of the industrial chain. At present, China's pharmaceutical packaging machinery industry accounts for 55.7% of the pharmaceutical equipment industry, and the market size has exceeded 100 billion yuan. It can be said that China's pharmaceutical packaging machinery industry has a broad market space in the future, and there is still huge potential to tap.

一：Packing material selection

Traditional pharmaceutical packaging materials are generally based on PVC as a hard sheet, its thickness is about 25-30C (0.25-0.3mm), such as PVC, PVC/PVDC, PVC/PE/PVDC, PVC/PE, in addition to high barrier requirements, few other special requirements. The emerging blister packaging puts forward additional appearance and processing performance requirements for packaging materials (appearance requirements such as: adjustable color, matte production, skin surface, etc.; Processing performance requirements such as: blister hard texture, forming depth, material tensile uniformity), so the chemical composition and processing performance of the packaging material must be significantly different from that of traditional pharmaceutical packaging materials. The types, properties and applications of common blister packaging materials are shown in Table 1, according to which packaging materials can be purchased.

Some new blister packaging tends to choose PET with better processing performance as the package material, because PET thickness is generally above 50C (or even 75C), so its molding and cutting is more difficult; The application of PVC/PVDC, which also has high barrier properties but lower cost than cold aluminum, is increasing; Although the traditional aluminum packaging can meet the requirements of high-grade appearance and high barrier, its shortcomings of easy extrusion deformation and high cost limit its application in cosmetics and other industries; Traditional capsule blister pattern printing requirements, no need to mark, most of the new blister need to mark, or even double marking, the stability of the equipment requirements

二：Forming depth

The depth of the traditional capsule blister is about 3-10mm, and the depth requirements of the emerging blister are far beyond this range

1. The depth of most liquid daily cosmetics blister is up to 25mm, and even the depth of some medical device blister packaging needs to be 60mm.

2. For the consideration of instrument testing, some medical test paper blister packaging is long, its depth is generally less than 3mm, and the spacing between the blister and the blister is even only 2mm, which puts forward new requirements for the hard plastic molding process, the accuracy of the mold, the precision of the pointer point cutting, and the toughness of the material.

三：Blanking method

The traditional medicine bag generally uses the tablet capsule feeder, this feeding method will inevitably appear the bubble bag empty situation, have to manually fill the material, so the vibration feeder, drum feeder, gate feeder and empty capsule visual identification system came into being, but the emergence of these feeder still can not meet the industry's increasingly rich blister packaging needs. For example, we will take into account the viscosity, pH and filling accuracy of the liquid cream. Most of the medical devices, electronic cigarette industry products are shaped, we use the most original manual feeding method, high automation requirements for customers we will install mechanical arms or spider hands according to the actual situation of the product

四：Sealed opening mode

From the principle point of view, the blister packaging machine sealing method are hot sealing, but the traditional pill can be directly opened by hand aluminum cover film, the sealing method of the equipment is not high, and the blister industry not only requires a firm seal, but also tore beautiful; Some blister opening mode is even directly broken, which also makes the blister packaging machine develop in the direction of non-standard customization; The design of the mold needs to reserve easy to tear and break bits; The selection of package materials puts forward higher requirements.

1, blister packaging machine is a multi-functional packaging machine, each packaging process are carried out at different stations.

The packaging machine is provided with a number of film conveying mechanisms, whose role is to transport the film and make it pass through the above stations to complete the blister packaging process.

The conveying mechanism of the blister packaging machine has a groove wheel mechanism, a CAM rocker mechanism, a CAM indexing mechanism, a ratchet mechanism, etc., which can be selected according to the accuracy of the conveying position, the acceleration curve and the adaptability of the packaging material.

2, heating will heat the molding film to a temperature that can be thermoformed processing, this temperature is determined according to the selection of packaging materials. For hard pvc, the temperature range that is easier to form is 110 ~ 130 ° C. The pvc film in this range has sufficient thermal strength and elongation.

The temperature has an impact on the thermoforming processing effect and the ductility of the packaging material, so the temperature control is required to be quite accurate.

However, it should be noted that the temperature referred to here is the actual temperature of the pvc film, which is directly measured on the surface of the film with a point thermometerBlister machine is a typical form of solid preparation packaging, it is a small dose plate packaging suitable for patients to use, with light weight, easy to carry, good sealing, drugs do not mix, service does not waste and other advantages, has become the mainstream of solid preparation packaging in China, in the pharmaceutical field has been widely used. The equipment used for blister packaging is called blister packaging machine, because the materials used are mostly plastic film and aluminum foil, it is also called aluminum plastic blister machine.Flat blister packaging machine working principle:

1, the plastic film is heated and softened by the heating device, and the softened film is blown into a blister by compressed air in the molding device (different blister shapes are achieved by replacing the molding mold);

2, filling and filling device will fill the material into the bubble cap (different material forms, filling device is different);

3, and then sent to the sealing device, under the appropriate temperature and pressure will cover the film and blister seal, and then through the typing embossing device to print on the batch number and press out broken lines or easy to break lines;

4, the final punching device punching into the specified size of the product plate.